Description
Sumatriptan belongs to a group of medicines called triptans. It acts on specific serotonin receptors, helping reverse the widening of blood vessels around the brain and reduce migraine-related nerve signalling.
What it is used for
Oral sumatriptan is used for the acute treatment of diagnosed migraine, with or without aura. It can relieve headache and associated symptoms such as nausea and sensitivity to light or sound.
Side effects
Common effects include dizziness, drowsiness, flushing, nausea, weakness and sensations of tingling, heaviness or pressure.
Seek urgent medical help for severe or persistent chest pain, breathing difficulties, facial or throat swelling, seizures or stroke-like symptoms. This list is not exhaustive. Do not drive if dizzy or sleepy.
Sumatriptan is unsuitable for people with certain heart or circulation conditions, previous stroke or transient ischemic attack, uncontrolled hypertension or severe liver disease. It must not be combined with other triptans or ergotamine medicines without the required intervals, or used within two weeks of an MAOI. Some antidepressants increase the risk of serotonin syndrome.
Recommended dosage
The usual adult starting dose in UK guidance is 50 mg; some patients require 100 mg. Take the prescribed dose when the migraine headache starts.
If the first dose provides relief but symptoms return, another dose may be taken after at least two hours. If the first dose provides no relief, do not repeat it for the same attack. The UK reference maximum is 300 mg in 24 hours. Frequent use can worsen headaches and requires review.
Storage guidelines
Store in a cool, dark place. Keep out of children’s sight and reach and do not use after expiry.
