Description
Zopiclone increases the effects of GABA, a chemical that reduces activity in the brain. This produces a sedative effect. Treatment should include an agreed duration and a plan for stopping.
What it is used for
The UK reference product is authorised for short-term insomnia in adults. It is not intended for routine long-term treatment.
Side effects
Common effects include a bitter or metallic taste, dry mouth and sleepiness. Dizziness, poor coordination and memory problems can also occur.
Seek emergency help for slow breathing, collapse or a severe allergic reaction. Stop taking it and contact a clinician immediately if sleepwalking, sleep-driving or other activities occur without full awareness. This list is not exhaustive.
Avoid alcohol. Combining zopiclone with opioids or other sedatives can cause dangerous breathing suppression. It is unsuitable in conditions including severe sleep apnoea, severe respiratory failure, myasthenia gravis and severe liver impairment. Do not drive for at least 12 hours after a dose, or whenever impaired.
Recommended dosage
The usual adult dose is 7.5 mg immediately before bed, once per night. Do not repeat the dose that night. Older adults and certain patients with kidney, liver or breathing problems generally start at 3.75 mg. Treatment ordinarily lasts no more than four weeks, including withdrawal. Follow the prescription; stopping may require gradual reduction.
Storage guidelines
Store in a cool, dark place. Keep out of children’s sight and reach and do not use after expiry.
